You can use the MeSH database to build a search from scratch. Although you are using the MeSH database, you can still integrate your own terms (keywords) into the strategy, but this must be the last thing you do after your MeSH terms have been entered, otherwise your additional text will be lost.
Remember, if you want to add your own words, you can also type into the PubMed Search Builder box, but only once all your MeSH terms are entered, otherwise your additional text will be lost as soon as you add a further MeSH term.
If you are adding your own terms to the seach, be careful to: